Aponvie : first intravenous P/neurokinin-1 (NK) receptor antagonist
- It was a brilliant idea that it significantly enhanced the efficacy of the generic drug by changing the route of administration.
- Aponvie’s fast onset of action, and half-life in human brain and convenience for patients (compliance perspective) seem very strong.
- However, the market penetration of Aponvie will be deecided by its price becausue generic drugs are much cheaper.
- Cancer patients spend high cost for their treatments and suffer from bills from hospitals and pharmacies. I am not confident they have enough room in their pockets to spend extra money for treating side effects of chemotherapy because side effects are just side effects, not directly related to “life or death matter.”
Zynrelef : postoperative pain reliever
- Zynrelef seems very promosinf and sounds really a next blockbuster because it can alternate opoids.
- Zynrelef can be injected in the surgery wound and its pain relieving effect can last up to 72 hours, and patients will feel nothing or less pain. 참고 자료:
https://www.fiercepharma.com/pharma/heron-scores-fda-go-ahead-aponvie-iv-alternative-pills-postoperative-nausea
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